Symptoms: Hypoglycaemia is not normally a problem encountered with Metformin when used in alone. In combination therapy with sulfonylurea or insulin with alcohol, hypoglycemia can occur. In excessive dosage and particularly, if there is a possibility of accumulation, lactic acidosis should be suspected. Some of the signs & symptoms suggestive of this condition are nausea, diarrhea, abdominal pain and dyspnea.
Treatment: Intensive supportive therapy is recommended which should be particularly directed at correcting fluid loss and metabolic disturbance.